产品概述:Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
靶点/蛋白:Human TRPC1.
来源:Goat
参考文献:Zhu X.,et al.FEBS Lett. 373:193-198(1995).Wes P.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:9652-9656(1995).Zitt C.,et al.Neuron 16:1189-1196(1996).Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Lockwich T.P.,et al.J. Biol. Chem. 275:11934-11942(2000).
特异性:Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Horse, Bovine, Dog
简单描述:Goat Polyclonal TRPC1 Antibody (Internal). Validated for use in IHC-P.
详情:FunctionThought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.Cellular_LocationMembrane; Multi-pass membrane protein.Tissue_LocationSeems to be ubiquitous.