产品概述:SH3D20 is a rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).
靶点/蛋白:This SH3D20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human SH3D20.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109(2010)
特异性:Human
别名:Rho GTPase-activating protein 27, CIN85-associated multi-domain-containing Rho GTPase-activating protein 1, Rho-type GTPase-activating protein 27, SH3 domain-containing protein 20, ARHGAP27, CAMGAP1, SH3D20
应用:WB~~1:2000
简单描述:Rabbit Polyclonal SH3D20 Antibody (Center). Validated for use in WB, E.
详情:FunctionRho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).Cellular_LocationCytoplasm. Membrane; Peripheral membrane proteinTissue_LocationExpressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer