产品概述:May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.
靶点/蛋白:JM4 Antibody detects endogenous levels of total JM4 protein.
来源:Rabbit
参考文献:Strom T.M.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.Schweneker M.,et al.FEBS Lett. 579:1751-1758(2005).
简单描述:Rabbit Polyclonal PRAF2 Antibody (aa129-178). Validated for use in WB, IHC-P, E.
详情:FunctionMay be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.Cellular_LocationEndosome membrane; Multi-pass membrane proteinTissue_LocationStrong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non- neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.