产品概述:Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.
靶点/蛋白:EDA1 antibody is human, mouse and rat reactive. Multiple isoforms of EDA1 are known to exist.
简单描述:Rabbit Polyclonal EDA / ED1 Antibody (Internal). Validated for use in WB, IHC-P, IF, E.
详情:FunctionSeems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.Cellular_LocationCell membrane; Single-pass type II membrane proteinTissue_LocationNot abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. {ECO:0000269|Ref.6}