产品概述:This gene encodes the alpha chain of type XXI collagen, amember of the FACIT collagen family (fibril-associated collagenswith interrupted helices). Type XXI collagen is localized totissues containing type I collagen so, like other members of thiscollagen family, it may serve to maintain the integrity of theextracellular matrix. An alternatively spliced transcript varianthas been described, but its full-length nature has yet to bedetermined.
靶点/蛋白:This COL21A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the N-terminal region of human COL21A1.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Chou, M.Y., et al. Genomics 79(3):395-401(2002)Tuckwell, D. Matrix Biol. 21(1):63-66(2002)Fitzgerald, J., et al. FEBS Lett. 505(2):275-280(2001)
特异性:Human
别名:Collagen alpha-1(XXI) chain, COL21A1, COL1AL
应用:WB~~1:1000IHC-P~~1:10~50IF~~1:10~50
简单描述:Rabbit Polyclonal COL21A1 Antibody (N-term). Validated for use in WB, IHC-P, IF, E.
详情:Cellular_LocationSecreted, extracellular space, extracellular matrix. Cytoplasm. Note=Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscleTissue_LocationHighly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta; moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium