产品概述:Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF? and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.
靶点/蛋白:This CHADL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-434 amino acids from the Central region of human CHADL.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Barbe, L., et al. Mol. Cell Proteomics 7(3):499-508(2008)
特异性:Human
别名:Chondroadherin-like protein, CHADL, SLRR4B
应用:WB~~1:1000
简单描述:Rabbit Polyclonal CHADL Antibody (Center). Validated for use in WB, E.