产品概述:Sulfatases (EC 3.1.5.6), such as ARSI, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules
靶点/蛋白:This ARSI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human ARSI.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Oshikawa, M., et al. Mol. Vis. 15, 482-494 (2009) Obaya, A.J. Gene 372, 110-117 (2006) Sardiello, M., et al. Hum. Mol. Genet. 14(21):3203-3217(2005)
特异性:Human
别名:Arylsulfatase I, ASI, 316-, ARSI
应用:WB~~1:1000FC~~1:10~50
简单描述:Rabbit Polyclonal ARSI Antibody (C-term). Validated for use in WB, FC, E.
详情:FunctionDisplays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts.Cellular_LocationSecreted. Endoplasmic reticulum Note=Localized in the intracellular granular structuresTissue_LocationExpressed in placenta, in embryonic stem cells, fetal eyes and lens.