产品概述:G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
靶点/蛋白:Human 5HT1F Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TPRXL (47%).
简单描述:Rabbit Polyclonal HTR1F / 5-HT1F Receptor Antibody (Cytoplasmic Domain). Validated for use in IHC-P.
详情:FunctionG-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.Cellular_LocationCell membrane; Multi-pass membrane protein