产品概述:The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
靶点/蛋白:This CBR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the C-terminal region of human CBR4.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Chen, Z., et al. FASEB J. 23(11):3682-3691(2009)Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :Endo, S., et al. Biochem. Biophys. Res. Commun. 377(4):1326-1330(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)
特异性:Human
别名:Carbonyl reductase family member 4, 1---, 3-oxoacyl-[acyl-carrier-protein] reductase, 111-, Quinone reductase CBR4, CBR4
应用:WB~~1:1000
简单描述:Rabbit Polyclonal CBR4 Antibody (C-term). Validated for use in WB, E.
详情:FunctionThe heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).Cellular_LocationMitochondrion matrixTissue_LocationDetected in liver and kidney (at protein level).