CB1 (aa44-58) Antibody (internal region, near N-Term)
供应商:
安诺伦(北京)生物科技有限公司
规格:
0.1 mg
商品分类:多克隆抗体
产品概述:This antibody is expected to recognize both reported isoforms (NP_057167.2; NP_149421.2). Reported variants represent identical protein: NP_001153731.1, NP_001153732.1, NP_057167.2, NP_001153730.1, NP_001153698.1
来源:Goat
存储溶液:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
参考文献:Binding of the hemopressin peptide to the cannabinoid CB1 receptor:structural insights. Scrima M, Di Marino S, Grimaldi M, Mastrogiacomo A, Novellino E, Bifulco M,D'Ursi AM. Biochemistry. 2010 Dec 14;49(49):10449-57. PMID: 21062041
简单描述:Goat Polyclonal CB1 (aa44-58) Antibody (internal region, near N-Term). Validated for use in WB, E.
详情:FunctionInvolved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.Cellular_LocationCell membrane; Multi-pass membrane protein.Tissue_LocationWidely expressed.