产品概述:The protein encoded by this gene is a chemokine receptorbelonging to the G protein-coupled receptor superfamily. The familymembers are characterized by the presence of 7 transmembranedomains and numerous conserved amino acids. This receptor is mostclosely related to RBS11 and the MIP1-alpha/RANTES receptor. Ittransduces a signal by increasing the intracellular calcium ionslevel. The viral macrophage inflammatory protein-II is anantagonist of this receptor and blocks signaling. Two alternativelyspliced transcript variants encoding the same protein have beenfound for this gene.
靶点/蛋白:This XCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-333 amino acids from the C-terminal region of human XCR1.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Yamazaki, C., et al. Biochem. Biophys. Res. Commun. 397(4):756-761(2010)Crozat, K., et al. J. Exp. Med. 207(6):1283-1292(2010)Bachem, A., et al. J. Exp. Med. 207(6):1273-1281(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Luttichau, H.R. Virol. J. 5, 50 (2008) :
简单描述:Rabbit Polyclonal XCR1 Antibody (C-term). Validated for use in WB, E.
详情:FunctionReceptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level.Cellular_LocationCell membrane; Multi-pass membrane protein.