产品概述:May act as soluble receptor for class I MHC antigens.
靶点/蛋白:This LILRA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human LILRA3.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Zhang Z., et al. Protein Sci. 13:2819-2824(2004).Arm J.P., et al. J. Immunol. 159:2342-2349(1997).Borges L., et al. J. Immunol. 159:5192-5196(1997).Norman P.J., et al. Immunogenetics 55:165-171(2003).
特异性:Human
别名:Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4
应用:WB~~1:1000
简单描述:Rabbit Polyclonal LILRA3 Antibody (C-term). Validated for use in WB, E.
详情:FunctionActs as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS- induced TNF-alpha production by monocytes.Cellular_LocationSecreted.Tissue_LocationDetected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.