产品概述:By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).
来源:Goat
存储溶液:0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
参考文献:Molecular analysis of NTB-A signaling: a role for EAT-2 in NTB-A-mediated activation of human NK cells. Eissmann P, et al. J Immunol, 2006 Sep 1. PMID 16920955.The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.The SLAM family of immune-cell receptors. Veillette A, et al. Curr Opin Immunol, 2003 Jun. PMID 12787752.
特异性:Human
别名:SH2 domain-containing protein 1B, EWS/FLI1-activated transcript 2, EAT-2, SH2D1B, EAT2
简单描述:Goat Polyclonal Goat Anti-EAT2 phospho (Y127) Antibody. Validated for use in WB, E.
详情:FunctionPlays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells.