别名:Ran GTPase-activating protein 1, RanGAP1, RANGAP1, KIAA1835, SD
应用:IHC-P (1:100), WB (1:500-1:1000),
简单描述:Rabbit Polyclonal RANGAP1 Antibody. Validated for use in WB, IHC-P, IF.
详情:FunctionGTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state.Cellular_LocationCytoplasm. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole. Note=Cytoplasmic during interphase. Targeted to the nuclear rim after sumoylation. During mitosis, associates with mitotic spindles. Association with kinetochores appears soon after nuclear envelope breakdown and persists until late anaphase Mitotic location also requires sumoylationTissue_LocationHighly expressed in brain, thymus and testis.