产品概述:LIAR Antibody: Ankyrin (ANK) repeats mediate protein-protein interactions in diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20. ANK repeats may occur in combinations with other types of domains. The structural repeat unit contains two anti-parallel helices and a beta-hairpin, with repeats stacked in a superhelical arrangement. LIAR, also known as ANKRD54, is a recently identified ANK repeat-containing protein that is predominantly expressed in tissues rich in cilliated cells, such as olfactory sensory neurons and is predicted to be important to cilia. At least three isoforms of LIAR are known to exist.
靶点/蛋白:ANKRD54;
来源:Rabbit
参考文献:Li J, Mahajan A, and Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry2006; 45:15168-78.
特异性:Human, Mouse, Rat
简单描述:Rabbit Polyclonal LIAR Antibody. Validated for use in WB, IHC-P, IF, E.
详情:FunctionPlays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.Cellular_LocationNucleus. Cytoplasm. Midbody. Note=Shuttles between nucleus and cytoplasm during the cell cycle. EPO stimulation induces nuclear accumulation (By similarity).