产品概述:The protein encoded by the gene is a cysteine proteinaseand a member of the papain superfamily. This proteolytic enzyme isinvolved in cellular protein degradation and turnover. Therecombinant form of this enzyme was shown to degrade syntheticpeptides typically used as substrates for cysteine proteinases andits proteolytic activity was abolished by an inhibitor of cyteineproteinase.
靶点/蛋白:This CTSO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human CTSO.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Roeske, D., et al. Mol. Psychiatry (2009) In press :Lamesch, P., et al. Genomics 89(3):307-315(2007)Santamaria, I., et al. Genomics 53(2):231-234(1998)Shi, G.P., et al. FEBS Lett. 357(2):129-134(1995)Velasco, G., et al. J. Biol. Chem. 269(43):27136-27142(1994)
特异性:Human
别名:Cathepsin O, CTSO, CTSO1
应用:WB~~1:1000IHC-P~~1:10~50
简单描述:Rabbit Polyclonal CTSO Antibody (N-term). Validated for use in WB, IHC-P, E.
详情:FunctionProteolytic enzyme possibly involved in normal cellular protein degradation and turnover.Cellular_LocationLysosome.Tissue_LocationExpressed in all tissues examined. High levels seen in the ovary, kidney and placenta while low levels seen in thymus and skeletal muscle