Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名:
MTA3 Antibody (C-term)
供应商:
安诺伦(北京)生物科技有限公司
商品分类:多克隆抗体
产品概述:MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.
靶点/蛋白:This MTA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-587 amino acids from the C-terminal region of human MTA3.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Bruning, A., et al. Histochem. Cell Biol. 132(1):33-38(2009)Lasky-Su, J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1345-1354 (2008) :Zhang, H., et al. Genes Dev. 20(21):2943-2948(2006)Yu, J.C., et al. J. Biomed. Sci. 13(3):419-432(2006)Fujita, N., et al. Cell 119(1):75-86(2004)
特异性:Human
别名:Metastasis-associated protein MTA3, MTA3, KIAA1266
应用:WB~~1:1000
简单描述:Rabbit Polyclonal MTA3 Antibody (C-term). Validated for use in WB, E.
详情:FunctionPlays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.Cellular_LocationNucleus {ECO:0000255|PROSITE- ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:12705869}Tissue_LocationExpressed in germinal centers of lymphoid tissues. No expression in nonepithelial cells