Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名:
MMP15 Antibody (N-term)
供应商:
安诺伦(北京)生物科技有限公司
商品分类:多克隆抗体
产品概述:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP15 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.
靶点/蛋白:This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the N-terminal region of human MMP15.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
参考文献:Jung, M., et al., Prostate 55(2):89-98 (2003).Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).d'Ortho, M.P., et al., Eur. J. Biochem. 250(3):751-757 (1997).Sato, H., et al., Genomics 39(3):412-413 (1997).Mattei, M.G., et al., Genomics 40(1):168-169 (1997).
简单描述:Rabbit Polyclonal MMP15 Antibody (N-term). Validated for use in WB, IHC-P, FC, E.
详情:FunctionEndopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.Cellular_LocationMembrane; Single-pass type I membrane protein; Extracellular sideTissue_LocationAppeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle