Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名:
REG3A Antibody (N-term)
供应商:
安诺伦(北京)生物科技有限公司
规格:
400 μl
商品分类:多克隆抗体
产品概述:REG3A encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this protein is observed during pancreatic inflammation and liver carcinogenesis.
靶点/蛋白:This REG3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human REG3A.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Medveczky,P., et.al., Biochem. J. 420 (2), 335-343 (2009)Scott,L.J., et.al, Proc. Natl. Acad. Sci. U.S.A. 106 (18), 7501-7506 (2009)Mukherjee,S., et.sl., J. Biol. Chem. 284 (8), 4881-4888 (2009)
特异性:Human
别名:Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha, Regenerating islet-derived protein 3-alpha 165 kDa form, Regenerating islet-derived protein 3-alpha 15 kDa form, REG3A, HIP, PAP, PAP1
应用:WB~~1:1000FC~~1:10~50
简单描述:Rabbit Polyclonal REG3A Antibody (N-term). Validated for use in WB, FC, E.
详情:FunctionBactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.Cellular_LocationSecreted. Note=Found in the apical region of pancreatic acinar cellsTissue_LocationHighly expressed in epidermal keratinocytes of psoriasis patients (at protein level). Constitutively expressed in intestine. Low expression is found in healthy pancreas Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.