Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名:
RAB8B Antibody (C-term)
供应商:
安诺伦(北京)生物科技有限公司
商品分类:多克隆抗体
产品概述:RAB proteins, like RAB8B, are low molecular mass monomericGTPases that localize on the cytoplasmic surfaces of distinctmembrane-bound organelles. RAB proteins function in intracellularvesicle transport by aiding in the docking and/or fusion ofvesicles with their target membranes (summary by Chen et al., 1997[PubMed 9030196]).
靶点/蛋白:This RAB8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-198 amino acids from the C-terminal region of human RAB8B.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Heidrych, P., et al. Hum. Mol. Genet. 17(23):3814-3821(2008)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Lau, A.S., et al. Endocrinology 144(4):1549-1563(2003)Hattula, K., et al. Mol. Biol. Cell 13(9):3268-3280(2002)
特异性:Human
别名:Ras-related protein Rab-8B, RAB8B
应用:WB~~1:1000
简单描述:Rabbit Polyclonal RAB8B Antibody (C-term). Validated for use in WB, E.
详情:FunctionThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).Cellular_LocationCell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid- anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis