Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名:
MMP8 Antibody (N-term)
供应商:
安诺伦(北京)生物科技有限公司
规格:
400 μl
商品分类:多克隆抗体
产品概述:Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is stored in secondary granules within neutrophils and isactivated by autolytic cleavage. Its function is degradation oftype I, II and III collagens. The gene is part of a cluster of MMPgenes which localize to chromosome 11q22.3.
靶点/蛋白:This MMP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMP8.
来源:Rabbit
存储溶液:Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:Li, Y., et al. J. Surg. Res. 163 (2), E99-E104 (2010) :Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Alexander, J.S., et al. Mult. Scler. 16(7):801-809(2010)Djuric, T., et al. J. Clin. Lab. Anal. 24(4):246-251(2010)
简单描述:Rabbit Polyclonal MMP8 Antibody (N-term). Validated for use in WB, E.
详情:FunctionCan degrade fibrillar type I, II, and III collagens.Cellular_LocationCytoplasmic granule. Secreted, extracellular space, extracellular matrix. Note=Stored in intracellular granulesTissue_LocationNeutrophils.