Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名:
GZMB / Granzyme B Antibody (N-Terminus)
供应商:
安诺伦(北京)生物科技有限公司
规格:
50 μl
商品分类:多克隆抗体
产品概述:This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
简单描述:Rabbit Polyclonal GZMB / Granzyme B Antibody (N-Terminus). Validated for use in IHC-P.
详情:FunctionThis enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.Cellular_LocationCytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells