产品概述:Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
靶点/蛋白:Detects ~100 kD protein.
来源:Mouse
参考文献:Murphy C.T.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.Xu S.-Z.,et al.Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.Aptel H.,et al.Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.Schmutz J.,et al.Nature 431:268-274(2004).Lussier M.P.,et al.J. Biol. Chem. 280:19393-19400(2005).
简单描述:Mouse Monoclonal TRPC7 Antibody (aa845-862, clone S64A-36). Validated for use in WB, IHC-P, IF, ICC, IP. Clone: S64A-36.
详情:FunctionThought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.Cellular_LocationCell membrane; Multi-pass membrane protein. Nucleus envelope