产品概述:Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
靶点/蛋白:ARHGEF1 (AAH34013.2, 830 a.a. ~ 927 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
来源:Mouse
存储溶液:Clear, colorless solution in phosphate buffered saline, pH 7.2.
参考文献:1.Loss of lsc/p115-protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice.Zizer E, Beilke S, Bauerle T, Schilling K, Mohnle U, Adler G, Fischer KD, Wagner M.Gastroenterology. 2010 Jun 20. [Epub ahead of print]