靶点/蛋白:Rat anti-CCT delta antibody, clone PK/9/86b recognises the delta polypeptide of the CCT chaperonin molecule complex, also known as CCTδ, CCT4 or stimulator of TAR RNA-binding. CCTδ is a 538 amino acid ~60 kDa molecular chaperone.The intact CCT complex is composed of eight polypeptides in a double-ring structure. CCT is important within cells in aiding the folding of proteins including actin, tubulin and the VHL tumour suppressor protein.
来源:Rat
参考文献:1. Hynes, G. et al. (1996) Analysis of chaperonin-containing TCP-1 subunits in the human keratinocyte two-dimensional protein database: further characterisation of antibodies to individual subunits.Electrophoresis. 17 (11): 1720-7. 2. Llorca, O. et al. (2000) Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations.EMBO J. 19 (22): 5971-9. 3. Hynes, G.M. & Willison, K.R. (2000) Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin.J Biol Chem. 275 (25): 18985-94.
特异性:' + item.reactivity + '
别名:T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta, Stimulator of TAR RNA-binding, CCT4, CCTD, SRB
简单描述:Rat Monoclonal Anti-CCT delta Antibody, clone PK/9/86b . Validated for use in WB, IP, GS. Clone: PK/9/86b.