产品概述:This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
来源:Mouse
参考文献:Herpers MJ et. Al. 1986, Acta Neuropathol, 70:333-339. | Van Muijen GN et. al. 1987, Lab Invest, 57:359-369. | Debus E, et. al. 1983, Differentiation, 25(2):193-203. |
特异性:Human, Mouse, Rat, Rabbit, Pig, Chicken, Cow
别名:Glial fibrillary acidic protein, GFAP, GFAP
简单描述:Mouse Monoclonal GFAP (Astrocyte & Neural Stem Cell Marker) Antibody. Validated for use in WB, IHC, IF, FC. Clone: GA-5.
详情:FunctionGFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.Cellular_LocationCytoplasm. Note=Associated with intermediate filamentsTissue_LocationExpressed in cells lacking fibronectin.