产品概述:Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8- mediated apoptosis.
靶点/蛋白:This BAP31 antibody is generated from a mouse immunized with a recombinant.
来源:Mouse
存储溶液:Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
参考文献:Mosser J.,et al.Genomics 22:469-471(1994).Li E.,et al.Eur. J. Biochem. 238:631-638(1996).Adachi T.,et al.EMBO J. 15:1534-1541(1996).Ota T.,et al.Nat. Genet. 36:40-45(2004).Ross M.T.,et al.Nature 434:325-337(2005).
特异性:Human
别名:B-cell receptor-associated protein 31, BCR-associated protein 31, Bap31, 6C6-AG tumor-associated antigen, Protein CDM, p28, BCAP31, BAP31, DXS1357E
应用:IHC-P~~1:25WB~~1:2000
简单描述:Mouse monoclonal BAP31 Antibody. Validated for use in IHC-P, WB, E. Clone: 1502CT208.31.16.
详情:FunctionFunctions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8- mediated apoptosis.Cellular_LocationEndoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complexTissue_LocationUbiquitous. Highly expressed in neurons and discrete endocrine cells.