参考文献:1. Cancer Res. 1992 Mar 15;52(6):1536-41 2. Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6071-5. 3. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3806-11.
简单描述:Mouse Monoclonal UBE1L Antibody. Validated for use in WB, E. Clone: 5B10.
详情:FunctionActivates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein.Tissue_LocationExpressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines