靶点/蛋白:Rat anti Mouse JAM-c antibody, clone CRAM-18 F26 recognises mouse and human Junctional adhesion molecule C (JAM-C), also known as JAM-3 and, historically, as JAM-2.JAM-C is expressed at junctions between endothelial and epithelial cells, as well as on leukocytes, platelets, vascular smooth muscle cells and fibroblasts, amongst other cell types. It plays a role in tight junctions and inflammatory processes and interacts with JAM-A and JAM-B.Clone CRAM-18 F26 has been reported to inhibit transendothelial migration (Johnson-Légeret al.2002).