产品概述:Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).
靶点/蛋白:Ni-NTA purified truncated recombinant STYK1-His is expressed in E. Coli strain BL21 (DE3)
简单描述:Mouse Monoclonal STYK1 Antibody (clone 2H2F10). Validated for use in WB, IHC-P, E. Clone: 2H2F10.
详情:FunctionProbable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).Cellular_LocationMembrane; Single-pass membrane proteinTissue_LocationWidely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers