产品概述:Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
靶点/蛋白:Specific for Mucin 16, also known as Ovarian Cancer Antigen CA-125. Recognizes epitope specificity group B (ISOBM classification) similar to M-11. Mucin 16 is a serum marker, overexpressed in epithelial ovarian cancer cells and is routinely used for ...
简单描述:Mouse Monoclonal MUC16 / CA125 Antibody (clone X75 (3C8/4)). Validated for use in WB, IHC-P, E. Clone: X75 (3C8/4).
详情:FunctionThought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.Cellular_LocationCell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domainTissue_LocationExpressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas