产品概述:The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
靶点/蛋白:Recognizes human keratin 14 at 50kD. Species cross-reactivity: Rat.
别名:Keratin, type I cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14, KRT14
应用:IHC-P (1:50), WB (1-2 μg/ml),
简单描述:Mouse Monoclonal KRT14 / CK14 / Cytokeratin 14 Antibody (C-Terminus). Validated for use in WB, IHC-P. Clone: .
详情:FunctionThe nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.Cellular_LocationCytoplasm. Nucleus. Note=Expressed in both as a filamentous patternTissue_LocationDetected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.