MUC5AC (Mucin 5AC / Gastric Mucin) Antibody - Without BSA and Azide
供应商:
安诺伦(北京)生物科技有限公司
规格:
100 μg
商品分类:单克隆抗体
产品概述:This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).āIts epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
来源:Mouse
存储溶液:200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
参考文献:Cancer Res.46: 3983-3989 (1986). | Biochem. J. 254: 185-193 (1988). | Int. J. Cancer 47: 304-310 (1991). |
特异性:Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Cat
别名:Mucin-5AC, MUC-5AC, Gastric mucin, Lewis B blood group antigen, LeB, Major airway glycoprotein, Mucin-5 subtype AC, tracheobronchial, Tracheobronchial mucin, TBM, MUC5AC, MUC5
简单描述:Mouse Monoclonal MUC5AC (Mucin 5AC / Gastric Mucin) Antibody - Without BSA and Azide. Validated for use in IHC-P, IF, FC. Clone: 45M1.
详情:FunctionGel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.Cellular_LocationSecreted.Tissue_LocationHighly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.