WNT7A Human

WNT7A Human

• WNT7A Human
• Wingless-Type MMTV Integration Site Family, Member 7A Human Recombinant
• 5µg ($50)
  20µg ($130)
  1mg ($2700)

   

CATALOGUE NUMBER

CYT-795

SYNONYMS

Wingless-Type MMTV Integration Site Family, Member 7A, Proto-Oncogene Wnt7a Protein, Protein Wnt-7a.

INTRODUCTION

Wingless-Type MMTV Integration Site Family, Member 7A also known as WNT7A belongs to the WNT gene family, this family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT7A is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays an essential role in uterine smooth muscle pattering and maintenance of adult uterine function. In addition, Mutations in WNT7A have been associated with Fuhrmann and Al-Awadi Raas-Rothschild Schinzel phocomelia syndromes.

DESCRIPTION

WNT7A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 341 amino acids (32-349 a.a) and having a molecular mass of 38kDa.
WNT7A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

SOURCE

Escherichia Coli.

PHYSICAL APPEARANCE

Sterile filtered colorless solution.

FORMULATION

WNT7A protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.

STABILITY

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. 
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

PURITY

Greater than 85.0% as determined by SDS-PAGE.

AMINO ACID SEQUENCE

MGSSHHHHHH SSGLVPRGSH MGSLGASIIC NKIPGLAPRQ RAICQSRPDA IIVIGEGSQM GLDECQFQFR NGRWNCSALG ERTVFGKELK VGSREAAFTY AIIAAGVAHA ITAACTQGNL SDCGCDKEKQ GQYHRDEGWK WGGCSADIRY GIGFAKVFVD AREIKQNART LMNLHNNEAG RKILEENMKL ECKCHGVSGS CTTKTCWTTL PQFRELGYVL KDKYNEAVHV EPVRASRNKR PTFLKIKKPL SYRKPMDTDL VYIEKSPNYC EEDPVTGSVG TQGRACNKTA PQASGCDLMC CGRGYNTHQY ARVWQCNCKF HWCCYVKCNT CSERTEMYTC K.

USAGE

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.