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- 详细信息
- 询价记录
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Resiquimod
- 库存:
10
- 供应商:
TargetMol
- CAS号:
144875-48-9
- 规格:
100 mg/1 mg/10 mg/1 g/200 mg/1 mL/5 mg/500 mg/50 mg/25 mg
| 规格: | 100 mg | 产品价格: | ¥1990.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥143.0 |
| 规格: | 10 mg | 产品价格: | ¥452.0 |
| 规格: | 1 g | 产品价格: | ¥5570.0 |
| 规格: | 200 mg | 产品价格: | ¥2680.0 |
| 规格: | 1 mL | 产品价格: | ¥523.0 |
| 规格: | 5 mg | 产品价格: | ¥297.0 |
| 规格: | 500 mg | 产品价格: | ¥3890.0 |
| 规格: | 50 mg | 产品价格: | ¥1360.0 |
| 规格: | 25 mg | 产品价格: | ¥725.0 |
Product Introduction
Bioactivity
英文名:Resiquimod
描述:Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans' cells, leading to an enhanced activation of T-lymphocytes.

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