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- ANT-182
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
1年
- 英文名：
Anthrax PA Polyclonal Antibody
- 库存：
大量
- 供应商：
上海沪震实业有限公司
- 规格：
200µl/400µl/600µl
CATALOGUE NUMBER
ANT-182
TYPE
Rabbit Anti Human Polyclonal Antibody.INTRODUCTION
Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2).FORMULATION
200µl PBS containing 0.05% BSA and 0.05% sodium azide.ISOTYPE
Rabbit Ig.IMMUNOGEN
Anthrax PA Antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 240-254 of the Anthrax PA protein (~83 kD). Anthrax PA Antibody is cleaved from the 83 kDa form to the 63 kDa form at amino acids 164-167. Thus the Anthrax PA antibody (made against amino acids 250-250) should recognize both the 83 kDa and 63 kDa PA forms, but not the 20 kDa cleavage fragment.APPLICATIONS
This polyclonal antibody can be used for detection of Anthrax PA protein in western blot, 1:1000.STABILITY
Store at 4°C, stable for 6 months. For long-term storage, store at -20°C.
USAGE
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验From Laboratory to Clinic: The Story of CAM PA TH-1
In 1890 it was shown that resistance to diphtheria toxin could be transferred from one animal to another by transfer of serum (1 ). From this discovery, passive antibody therapy was developed as an effective treatment for infectious diseases
Both botulinum neurotoxins (BoNTs) and anthrax lethal factor, a component of anthrax toxin, exhibit zinc metalloprotease activity. The assay detailed here is capable of quantitatively detecting these proteins by measuring their enzymatic
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠 组织纤溶酶原激活剂 (t-PA)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 t-PA 单抗包被于酶标板上，标准品和样品中的 t-PA 与单抗结合，加入生物素化的抗大鼠 t-PA ，形成免疫复合
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