重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A) 分子生

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产供应重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A) 分子生物学试剂，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A) 分子生物学试剂
品牌：百奥莱博
规格：10μg|50μg|500μg|1mg
产地：国产|进口
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu23-Tyr453在C端含有His标签。

SMPDL3A质量控制：＞95%(还原性SDS-PAGE)

SMPDL3A制剂：冻干品

SMPDL3A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SMPDL3A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SMPDL3A：
Acid sphingomyelinase-like phosphodiesterase 3a (SMPDL3A ) is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases.

欲了解更多重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A) 分子生物学试剂的品牌、产地、价格及说明书等产品信息，请致电北京百奥莱博科技有限公司，我们将竭诚为您服务，另外，以下产品正在火爆促销:

·重组人CD99(MIC2)
编号：JN1869
英文名称：Recombinant Human CD99
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp23-Asp122在C端带有Fc标签。

CD99/MIC2质量控制：＞95%(还原性SDS-PAGE)

CD99/MIC2制剂：冻干品

CD99/MIC2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD99/MIC2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD99/MIC2：
CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules. The extracellular domain of CD99 contains no identifiable motifs, its cytoplasmic region, although short, does have signal transduction capability. Cells known to express CD99 include fibroblasts, neutrophils, T cells, double positive thymocytes, CD34+ stem cells, monocytes and endothelial cells. Two types of CD99 isoforms have been classified. Native human CD99 is referred to as the long, or type I isoform. The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 amino acids. The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II), and mediate clearly different biological outcomes. Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation. Human CD99 has 48% aa sequence identity to mouse CD99.


重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A) 分子生物学试剂关键词：重组人SMPDL3A蛋白,JN1150,重组人酸性鞘磷脂酶如磷酸二酯酶3A,重组SMPDL3A


·重组人Reticulocalbin-3(Rcn3)(内质网*离子结合蛋白)
编号：JN0820
英文名称：Recombinant Human Reticulocalbin-3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Lys21-Leu328在C端含有His标签。

Reticulocalbin-3质量控制：＞95%(还原性SDS-PAGE)

Reticulocalbin-3制剂：液体

Reticulocalbin-3保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Reticulocalbin-3：
Reticulocalbin-3 is a member of the CREC family that is involved in the secretory pathway. Members of the CREC family consist of a number of multiple EF-hand domains. Reticulocalbin-3 localizes to the endoplasmic reticulum lumen. The bioinformaticanalysis of Reticulocalbin-3 reveal that it is a putative Ca2+-binding protein. In addition, it has been shown that autoactivation and secretion of PACE4 was increased upon co-expression with Reticulocalbin-3. The proPACE4-RCN-3 complex is plays an important role in the biosynthesis of PACE4.


重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A) 分子生物学试剂关键词：重组人SMPDL3A蛋白,JN1150,重组人酸性鞘磷脂酶如磷酸二酯酶3A,重组SMPDL3A

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