北京现货重组人CD33(Siglec-3)折扣价

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括北京现货重组人CD33(Siglec-3)折扣价在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：北京现货重组人CD33(Siglec-3)折扣价
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human Sialic Acid Binding Ig-like Lectin 3
品牌：百奥莱博
编号：JN1832
产地：国产|进口
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp18-His259在C端含有Fc标签和His标签

CD33/Siglec-3质量控制：＞95%(还原性SDS-PAGE)

CD33/Siglec-3制剂：冻干品

CD33/Siglec-3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD33/Siglec-3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD33/Siglec-3：
CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. CD33 related Siglecs have differential expression pattern within the hematopoietic system. They are involved in the regulation of cellular activation within the immune system. Siglec 3 expression is restricted to cells of myelomonocytic lineage. Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation.

更多有关北京现货重组人CD33(Siglec-3)折扣价的价格及使用说明等，请联系我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组小鼠DDR2
编号：JN1496
英文名称：Recombinant Mouse Discoidin domain-containing receptor 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln24-Arg399在C端含有His标签。

DDR2 质量控制：＞95%(还原性SDS-PAGE)

DDR2 制剂：冻干品

DDR2 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

DDR2 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于DDR2 ：
Discoidin domain receptor-2 (DDR2) is a cell surface tyrosine kinase receptor that can be activated by soluble collagen and has been implicated in diverse physiological functions including organism growth and wound repair. DDR2 binds to and is activated by collagen I, II, III, V, and X, with the notable exception of basement membrane collagen IV. DDR2 is expressed in connective tissues arising from embryonic mesoderm. DDR2 regulates cell proliferation, cell adhesion, migration, and extracellular matrix remodeling.


北京现货重组人CD33(Siglec-3)折扣价关键词：JN1832,重组CD33,重组人CD33蛋白,重组人Siglec-3


·重组人IL-12RB2
编号：JN1416
英文名称：Recombinant Human Interleukin-12 receptor subunit beta-2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Cys28-Asn622在C端带有Fc标签。

IL-12RB2质量控制：＞95%(还原性SDS-PAGE)

IL-12RB2制剂：冻干品

IL-12RB2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IL-12RB2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IL-12RB2：
The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits that are linked via disulfide bonds. Ligation of IL-12 to its receptor involves the binding of IL-12p35 to IL12RB1 and IL-12p40 to IL12RB2. This will result in the activation of tyrosine kinase 2 (TYK2), which is associated with the IL12RB1 chain and Janus kinase 2 (JAK2), which is associated with the IL12RB2 chain. Activated TYK2 and JAK2 direct the phosphorylation of STAT4. IL12RB1 is present on all lymphocytes, while the expression of IL12RB2 is tightly regulated. It has shown that the expression of IL12RB2 is limited to Th2 cells. IL12RB2 subunit plays an important role in Th1 cell differentiation, since its absence leads to an abortive Th1 differentiation that has dysfunctional production of Th1 effector molecules.


北京现货重组人CD33(Siglec-3)折扣价关键词：JN1832,重组CD33,重组人CD33蛋白,重组人Siglec-3

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我公司正在火爆促销分子生物学试剂系列产品，欢迎您的垂询选购北京现货重组人CD33(Siglec-3)折扣价。