特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")JN0933型重组人精*酸脱亚胺酶4(PAD4)(PADI4)哪里卖,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:JN0933型重组人精*酸脱亚胺酶4(PAD4)(PADI4)哪里卖
英文名:Recombinant Human Protein-Arginine Deiminase Type-4
品牌:百奥莱博
规格:10μg|50μg|500μg|1mg
编号:JN0933
产地:国产|进口
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Pro663在N端含有His标签。
PADI4质量控制:>95%(还原性SDS-PAGE)
PADI4制剂:液体
PADI4保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PADI4:
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
关于JN0933型重组人精*酸脱亚胺酶4(PAD4)(PADI4)哪里卖的更详细说明,请致电我公司咨询,我们将以最饱满的热情为您提供解答,此外,我公司专业供应下列产品:
·重组小鼠PD-1(程序化细胞死亡蛋白1)
编号:JN1895
英文名称:Recombinant Mouse Programmed Cell Death Protein 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Gln167在C端含有His标签。
PD-1质量控制:>95%(还原性SDS-PAGE)
PD-1制剂:冻干品
PD-1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PD-1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PD-1:
Programmed Death-1 (PD-1), firstly cloned from mouse T cell hybridoma 2B4.11, is one member of CD28/CTLA-4 superfamily. PD-1 belongs to type I transmembrane protein and acts as an important immunosuppressive molecule. The cytoplamsic tail of PD-1 contains two structural motifs, an immunoreceptor tyrosine-based inhibitory motif (ITIM) and an immunoreceptor tyrosine-based switch motif (ITSM) formed by two tyrosine residues which make the difference in PD-1 signal mediating.Mouse PD-1 is expressed in thymus and shares about 69% aa sequence identity with human PD-1. Recently, programmed death-1 (PD-1) with its ligands, programmed death ligand B7H1 (PD-L1) and B7DC (PD-L2), was found to regulate T-cell activation and tolerance, upon ligand binding, inhibiting T-cell effector functions in an antigen-specific manner.PD-1 gene knocked out mice would induce some autoimmune diseases, which suggests that PD-1 acts as a co-inhibitory molecule actively participating in maintaining peripheral tolerance. Thus, PD-1 may be a useful target for the immunologic therapy of carcinoma,infection,autoimmune diseases as well as organ transplantation.
JN0933型重组人精*酸脱亚胺酶4(PAD4)(PADI4)哪里卖关键词:JN0933,重组人PADI4,重组人精*酸脱亚胺酶4,重组人精*酸脱亚胺酶4蛋白,重组人PAD4
·重组人富含半胱*酸蛋白61(富含半胱*酸血管新生诱导剂61)(Cyr61)(CCN1)
编号:JN1089
英文名称:Recombinant Human Cysteine-rich angiogenic inducer 61
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Thr25-Asp381在C端带有Fc标签。
Cyr61/CCN1质量控制:>95%(还原性SDS-PAGE)
Cyr61/CCN1制剂:冻干品
Cyr61/CCN1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Cyr61/CCN1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Cyr61/CCN1:
Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10 , GIG1, CYR61, CCN1 and IGFBP10, belongs to the CCN family, CYR61 is a secreted protein and contains one CTCK (C-terminal cystine knot-like) domain,one IGFBP N-terminal domain,one TSP type-1 domain andone VWFC domain. CYR61 promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. CYR61 plays important roles in inflammation and tissue repair. CYR61 is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.
JN0933型重组人精*酸脱亚胺酶4(PAD4)(PADI4)哪里卖关键词:JN0933,重组人PADI4,重组人精*酸脱亚胺酶4,重组人精*酸脱亚胺酶4蛋白,重组人PAD4
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