重组人细胞毒性T淋巴细胞蛋白4(CTLA-4)(CD152)

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组人细胞毒性T淋巴细胞蛋白4(CTLA-4)(CD152)促销在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组人细胞毒性T淋巴细胞蛋白4(CTLA-4)(CD152)促销
英文名：Recombinant Human Cytotoxic T-lymphocyte protein 4
编号：JN1568
品牌：百奥莱博
规格：10μg|50μg|500μg|1mg
产地：国产|进口
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Lys36-Asp161在C端含有His标签。

CTLA-4/CD152质量控制：＞95%(还原性SDS-PAGE)

CTLA-4/CD152制剂：冻干品

CTLA-4/CD152保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CTLA-4/CD152复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CTLA-4/CD152：
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence, a 126 aa extracellular domain (ECD) with one Ig-like V-type domain, a 21 aa transmembrane (TM) sequence, and a 41 aa cytoplasmic sequence.It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

想要了解更多关于重组人细胞毒性T淋巴细胞蛋白4(CTLA-4)(CD152)促销的价格、品牌、厂家、说明书、促销信息，请和我们联系。此外我公司还销*(代"售")下面的产品：

·重组小鼠颗粒酶B(GZMB)
编号：JN1321
英文名称：Recombinant Mouse Granzyme B
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly19-Ser247在C端含有His标签。

GZMB质量控制：＞95%(还原性SDS-PAGE)

GZMB制剂：液体

GZMB保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于GZMB：
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp andseems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.


重组人细胞毒性T淋巴细胞蛋白4(CTLA-4)(CD152)促销关键词：重组人CTLA-4,JN1568,重组人细胞毒性T淋巴细胞蛋白4,重组人细胞毒性T淋巴细胞蛋白4蛋白,重组人CD152


·重组人FGF19(成纤维细胞生长因子19)(带His标签)
编号：JN0243
英文名称：Recombinant Human Fibroblast growth factor 19
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Phe27-Lys216在N端含有His标签

FGF-19质量控制：＞95%(还原性SDS-PAGE)。

FGF-19制剂：冻干品

FGF-19保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

FGF-19复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于FGF-19：
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.


重组人细胞毒性T淋巴细胞蛋白4(CTLA-4)(CD152)促销关键词：重组人CTLA-4,JN1568,重组人细胞毒性T淋巴细胞蛋白4,重组人细胞毒性T淋巴细胞蛋白4蛋白,重组人CD152


·重组小鼠Cystatin F(胱抑素F)
编号：JN1769
英文名称：Recombinant Mouse Cystatin F
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala19-Gln144在C端含有His标签。

Cystatin F质量控制：＞95%(还原性SDS-PAGE)

Cystatin F制剂：液体

Cystatin F保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Cystatin F：
Mouse Cystatin F belongs to cystatin superfamily, which encomp*(代"a")sses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a biomarker for both liver metastasis and inflammatory lung disorders. Mouse Cystatin F inhibits papain and cathepsin L but with affinities lower than other cystatins. It may play a role in immune regulation through inhibition of a unique target in the hematopoietic system.

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