重组人Fc gamma RIIIA(CD16a)(FCGR3

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人Fc gamma RIIIA(CD16a)(FCGR3A) 分子生物学试剂在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人Fc gamma RIIIA(CD16a)(FCGR3A) 分子生物学试剂
编号：JN1829
产地：国产|进口
英文名：Recombinant Human Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly17-Gln208在C端含有His标签。

Fc gamma RIIIA/CD16a/FCGR3A质量控制：＞95%(还原性SDS-PAGE)

Fc gamma RIIIA/CD16a/FCGR3A制剂：冻干品

Fc gamma RIIIA/CD16a/FCGR3A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Fc gamma RIIIA/CD16a/FCGR3A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Fc gamma RIIIA/CD16a/FCGR3A：
Receptors for the Fc region of immunoglobin G (FcγR) are divided into three classes and FcγRIII is a multifunctional, low/intermediate affinity receptor. In humans, FcγRIII is expressed as two distinct forms (FcγRIIIA and FcγRIIIB) that are encoded by two different but highly homologous genes in a cell type-specific manner. FcγRIIIB is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas FcγRIIIA is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. The FcγRIIIA receptor is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), mast cell degranulation, and clearance of immune complexes. FcγRIIIA has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. Aberrant expression or mutations in this gene is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. In humans, it is a 50 -70 kD type I transmembrane activating receptor. The FcγRIIIA cDNA encodes 254 amino acid including a 16aa signal sequence, 191 amino acid ECD with two C2-type Ig-like domains, five potential N-glycosylation sites, a 22 amino acid transmembrane sequence and a 25 amino acid cytoplasmic domain.


除重组人Fc gamma RIIIA(CD16a)(FCGR3A) 分子生物学试剂外，我公司正在打折促销以下产品：

·重组人血管紧张素转化酶2(ACE-2)
编号：JN0552
英文名称：Recombinant Human Angiotensin-Converting Enzyme 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln18-Ser740在C端含有His标签。

ACE-2质量控制：＞95%(还原性SDS-PAGE)


ACE-2制剂：液体

ACE-2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于ACE-2：
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.


重组人Fc gamma RIIIA(CD16a)(FCGR3A) 分子生物学试剂关键词：JN1829,重组人CD16a,重组人Fc gamma RIIIA,重组人FCGR3A,重组人Fc gamma RIIIA蛋白


·重组人醛酮还原酶家族1成员C4(AKR1C4)
编号：JN0886
英文名称：Recombinant Human Aldo-Keto Reductase Family 1 Member C4
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Tyr323在N端含有His标签。

AKR1C4质量控制：＞95%(还原性SDS-PAGE)

AKR1C4制剂：液体

AKR1C4保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于AKR1C4：
Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.


重组人Fc gamma RIIIA(CD16a)(FCGR3A) 分子生物学试剂关键词：JN1829,重组人CD16a,重组人Fc gamma RIIIA,重组人FCGR3A,重组人Fc gamma RIIIA蛋白

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北京百莱博科技有限公司是分子生物学试剂产品的专业生产供应销*(代"售")商，恭候您的咨询选购重组人Fc gamma RIIIA(CD16a)(FCGR3A) 分子生物学试剂。