重组人泛素结合酶E2-S(UBE2S) 分子生物学试剂

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名称：重组人泛素结合酶E2-S(UBE2S) 分子生物学试剂
编号：JN0683
产地：国产|进口
品牌：百奥莱博
英文名：Recombinant Human Ubiquitin-Conjugating Enzyme E2 S
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu222在N端带有GST标签。

UBE2S质量控制：＞95%(还原性SDS-PAGE)

UBE2S制剂：液体

UBE2S保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBE2S：
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.

更多有关重组人泛素结合酶E2-S(UBE2S) 分子生物学试剂的价格及使用说明等，请联系我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组人CPB1(羧肽酶B1)
编号：JN1691
英文名称：Recombinant Human Carboxypeptidase B1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的His16-Tyr417在C端含有His标签。

CPB1质量控制：＞95%(还原性SDS-PAGE)

CPB1制剂：液体

CPB1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于CPB1：
Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.


重组人泛素结合酶E2-S(UBE2S) 分子生物学试剂关键词：重组人UBE2S,重组泛素结合酶E2-S,重组人泛素结合酶E2-S蛋白,JN0683


·重组小鼠脂肪细胞补体相关蛋白30(Acrp30)
编号：JN1183
英文名称：Recombinant Mouse Adipocyte complement-related 30 kDa protein
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Glu18-Asn247在N端含有His标签。

Acrp30质量控制：＞95%(还原性SDS-PAGE)

Acrp30制剂：冻干品

Acrp30保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Acrp30复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Acrp30：
Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.


重组人泛素结合酶E2-S(UBE2S) 分子生物学试剂关键词：重组人UBE2S,重组泛素结合酶E2-S,重组人泛素结合酶E2-S蛋白,JN0683


·重组人白介素IL-17A(白细胞介素17A)
编号：JN0337
英文名称：Recombinant Human Interleukin-17A
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Ile20-Ala155表达纯化而来。

IL-17/IL-17A质量控制：＞95%(还原性SDS-PAGE)。

IL-17/IL-17A制剂：冻干品

IL-17/IL-17A保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-17/IL-17A复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-17/IL-17A：
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.

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