This human apolipoprotein A1 (ApoA1) antigen assay is intended for the quantitative determination of total ApoA1 in human plasma, serum, urine & other biological fluids.
ApoA1 is the major protein constituent of high density lipoprotein which is the densest of the lipoprotein aggregates. ApoA1 participates in the reverse transport of cholesterol from tissues to the liver and is a cofactor for lecithin cholesterol acyl tranferase. The ratio of ApoA1 to Apolipoprotein B (ApoB), the primary component of low density lipoprotein, is an effective predictor of cardiovascular disease.