Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法
Affinity purification
亚型
IgG
免疫原
A synthetic peptide of human SOCS3
性状
Lyophilized or Liquid
Swiss Prot
O14543
克隆类型
Polyclonal Antibody
来源
Rabbit
背景资料
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.