Anti-PDE1A Polyclonal Antibody

英文名称Rabbit PDE1A Polyclonal Antibody别名ANKRD33应用WB稀释比例WB1:500-1:2000交叉反应Human,Mouse,Rat蛋白分子量61kDaGene ID5136保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.储存液PBS with 0.02% sodium azide, 50% glycerol, pH7.3.纯化方法Affinity purification亚型IgG免疫原Recombinant protein of human PDE1A性状Lyophilized or LiquidSwiss ProtP54750克隆类型Polyclonal Antibody来源Rabbit背景资料Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).