- $1902
- Alomone
- 以色列
- AK-213
- 2025年07月13日
- 见官方网站
- 见说明书
- 见官方网站
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- 详细信息
- 技术资料
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
液体或冻干粉
- 保存条件：
-20°C
- 克隆性：
多克隆
- 标记物：
见官方网站
- 适应物种：
见官方网站
- 保质期：
6个月
- 抗原来源：
见说明书
- 目录编号：
AK-213
- 级别：
高
- 库存：
大量
- 供应商：
上海信裕生物科技有限公司
- 宿主：
见说明书
- 应用范围：
见官方网站
- 浓度：
见官方网站
- 靶点：
见官方网站
- 抗体英文名：
AMPA Receptor Antibody Explorer Kit
- 抗体名：
AMPA Receptor Antibody Explorer Kit
- 规格：
22 Vials
AMPA Receptor Antibody Explorer Kit
A Screening Package of AMPA Receptor Antibodies Economically PricedCat #: AK-213
22 Vials
AMPA Receptor Antibody Explorer KitAlomone Labs is pleased to offer the AMPA Receptor Antibody Explorer Kit (#AK-213). The Explorer Kit contains AMPA receptor antibodies with their respective peptide control antigen. An ideal tool for screening purposes.
- Compounds
- Scientific Background
- Related Products
| Product Name | Cat # | Size |
|---|---|---|
Anti-AMPA Receptor 1 (GluA1) (extracellular) |
AGC-004 | 1 x 50 µl |
Anti-AMPA Receptor 2 (GluA2) (extracellular) |
AGC-005 | 1 x 50 µl |
Guinea pig Anti-AMPA Receptor 2 (GluA2) (extracellular) |
AGP-073 | 1 x 50 µl |
Anti-AMPA Receptor 3 (GluA3) (extracellular) |
AGC-010 | 1 x 50 µl |
Anti-AMPA Receptor 4 (GluA4) (extracellular) |
AGC-019 | 1 x 50 µl |
Anti-CaVγ2 |
ACC-012 | 1 x 50 µl |
Anti-CaVγ3 |
ACC-113 | 1 x 50 µl |
Anti-CaVγ4 |
ACC-114 | 1 x 50 µl |
Anti-CaVγ5 (extracellular) |
ACC-115 | 1 x 50 µl |
Anti-CaVγ7 (extracellular) |
ACC-109 | 1 x 50 µl |
Anti-CaVγ8 |
ACC-125 | 1 x 50 µl |
Note Guinea pig polyclonal antibodies (#AGP-009 & #AGP-073) are included in this Explorer Kit. Please take into account when reacting with a secondary antibody.
Scientific Background
The ionotropic glutamate receptors are divided into three main categories: AMPA, NMDA (N-methyl-D-aspartate) and Kainate Receptors.
AMPA Receptors consist of four closely related genes with a high sequence homology. Their related products, GluR1-GluR4 subunits combine in tetramers in different stoichiometries1 which determine their channel function. These receptors, like many other cellular proteins undergo post-translational modifications. Such modifications influence protein-protein interactions, trafficking, internalization and their accumulation in the Golgi. Also, post-translational modifications are also involved in regulating LTP-driven incorporation of AMPA Receptors into the post-synaptic membrane (extensively reviewed in reference 2).
AMPA Receptors are responsible for the primary depolarization in glutamate-mediated neurotransmission. in situ hybridization and immunocytochemistry studies show that AMPA Receptors are mainly distributed in the brain. These receptors play important roles in synaptic plasticity, excitatory neurotransmission, LTP and LTD effects, and take part in learning and memory formation3-6. The important functions AMPA Receptors have acquired, also imply that deregulation of these receptors leads to pathologies.
References
- Hollmann, M. et al. (1994) Annu. Rev. Neurosci. 17, 31.
- Santos, S.D. et al. (2009) Neuroscience 158, 105.
- Morris, R.G. (2006) Eur. J. Neurosci. 23, 2829.
- Pastalkova, E. et al. (2006) Science 313, 1141.
- Rumpel, S. et al. (2005) Science 308, 83.
- Whitlock, J.R. et al. (2006) Science 313, 1093.
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