- ¥960 - 1600
- 江蓝纯
- K002119P
- 2025年07月16日
9 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 库存：
99
- 供应商：
江蓝纯
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ¥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ¥1600.0 |
| 英文名称 | Rabbit CDKN2A Polyclonal Antibody |
|---|---|
| 别名 | ARA9;FKBP16;FKBP37;SMTPHN;XAP-2;XAP2 |
| 应用 | WB,IF |
| 稀释比例 | WB1:500-1:2000 IF1:50-1:200 |
| 交叉反应 | Human |
| 蛋白分子量 | 17kDa |
| Gene ID | 1029 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CDKN2A |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | P42771,Q8N726 |
| 克隆类型 | Polyclonal Antibody |
| 来源 | Rabbit |
| 背景资料 | This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Anti-CDKN2A Polyclonal Antibody
¥960 - 1600
