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- 英文名：
Recombinant Human BMP-13/CDMP-2
- 供应商：
研卉生物
- 规格：
50ug
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
Source: E.coli
Synonyms: Bone Morphogenetic Protein-13, GDF-6, Cartilage-Derived Morphogenetic Protein-2 (CDMP-2)
AA Sequence (monomer): TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/ml.
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文献和实验://pid.nci.nih.gov 简介：由NCI和Nature 共同创立，提供已知的人体细胞信号转导、调节活动及主要细胞生命过的蛋白质路径网，可通过输入某个分子名或代谢过程名称进行查询。 10.UniHI(Unified Human Interactome database) 网址：http://www.unihi.org 简介：人体蛋白-蛋白相互作用数据库，可根据蛋白质名称、代谢路径等进行查询。 11.VirHostNet
Electroporation of Human Lymphoblastoid Cells
There are many reasons to introduce new genes on recombinant vectors into mammalian cells. For example, in situ studies of the effects of particular gene products on DNA replication (1 –3 ), repair (4 –6 ), recombination (7 ), or gene
Human Chromosome Analysis and Sorting
and aneuploidies (13,21, and X) recognized. A flow karyotype shows a pattern of peaks and troughs that is unique for each individual or cell line because of the variation in heterochromatic regions of the chromosomes (2 ). When combined with family studies, flow
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