- ¥960 - 1600
- 江蓝纯
- K004316P
- 2025年07月08日
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- 详细信息
- 技术资料
- 库存：
99
- 供应商：
江蓝纯
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ¥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ¥1600.0 |
| 英文名称 | Rabbit ACO1 Polyclonal Antibody |
|---|---|
| 应用 | WB,IHC |
| 稀释比例 | WB1:500-1:1000 IHC1:50-1:100 |
| 交叉反应 | Mouse,Rat |
| 蛋白分子量 | 98kDa |
| Gene ID | 48 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ACO1 |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | P21399 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants |
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Anti-ACO1 Polyclonal Antibody
¥960 - 1600
