Anti-HRAS Polyclonal Antibody

Anti-HRAS Polyclonal Antibody

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  • ¥680 - 1600
  • 江蓝纯
  • K005541P
  • 2025年07月12日
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    • 详细信息
    • 技术资料
    • 库存

      99

    • 供应商

      江蓝纯

    • 规格

      30ul/50ul/100ul

    规格:30ul产品价格:¥680.0
    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    英文名称 Rabbit HRAS Polyclonal Antibody
    应用 WB,IHC
    稀释比例 WB1:500-1:2000 IHC1:50-1:200
    交叉反应 Human,Mouse,Rat
    蛋白分子量 21kDa
    Gene ID 3265
    保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
    储存液 PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 A synthetic peptide of human HRAS
    性状 Lyophilized or Liquid
    Swiss Prot P01112
    克隆类型 Polyclonal Antibody
    来源 Rabbit
    背景资料 This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

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